How to determine if it is diabetes or cancer recurrence

Now I will explain how to determine whether it is diabetes or cancer recurrence. I am happy to be able to help you, so let's begin. Diabetes is a cancer catalyst! Research: Liver cancer and pancreatic cancer have a two-fold higher risk. 【Dr. Lin Jiahong (Attending Physician in the Metabolism Department at Chang Gung Hospital in Linkou)】Complications of diabetes are a big question. Does diabetes always lead to complications?

，多项研究已经发现糖尿病患者患癌的风险更高。一方面，糖尿病患者的高血糖水平可能导致细胞内糖化作用增加，进而导致DNA损伤和癌变。另一方面，糖尿病患者常常伴随着肥胖，而肥胖也被证实与多种癌症的发生风险增加有关。此外，糖尿病患者的胰岛素水平较高，胰岛素本身也可能促进癌细胞的生长和扩散。因此，糖尿病与癌症之间存在着复杂而密切的联系。

为了预防和控制糖尿肥胖症以及减少癌症的发生风险，我们需要加强健康教育，推广健康饮食和生活方式。此外，定期体检、控制体重、保持适度的运动和合理的药物治疗都是预防和管理糖尿病和癌症的重要措施。只有全社会共同努力，才能揭开糖尿肥胖症与癌症之间的神秘连结，保障人民的健康。

Although diabetes has already caused a heavy burden on the economy and society, to make matters worse, numerous epidemiological studies have unanimously pointed out that diabetes is closely related to several types of cancer, especially breast cancer in women. In recent years, although the Chinese people have gradually realized that consuming excessive carbohydrates, especially refined starch, significantly increases the risk of obesity, metabolic syndrome, and even diabetes. However, what the general public is less aware of is that besides these metabolic disorders, consuming excessive carbohydrates also increases the probability of developing cancer, and it also reduces the effectiveness of treatment and survival rates for those already diagnosed with cancer.

Do cancer cells like to eat sugar? Yes, but it's not just that. Regarding the fact that excessive sugar can worsen and relapse cancer, there is an oversimplified statement: sugar is the favorite food of cancer cells. This statement actually only states a small part of the truth. The connection between sugar and cancer cells is far more complex than just being their favorite food. A study published in 2014 provides us with more accurate and precise information.

The conclusions of this study are as follows: 1. After surgery for breast cancer, if the intake of carbohydrates remains unchanged or increases, the recurrence rate of breast cancer will double. 2. If insulin-like growth factor-1 (IGF-1) is detected in the tumor, the recurrence rate increases by 70%.

3. However, if both of the above factors exist, the recurrence rate jumps to 5 times. The first conclusion of the study is enough to make us alert: after breast cancer treatment, it is necessary to adjust the intake of carbohydrates to avoid promoting cancer recurrence. However, the study mentions an important substance: IGF-1. What exactly is IGF-1? Why does it have such a significant impact on breast cancer recurrence? This needs to be explained starting from its origin - growth hormone.

Sugar and Cancer, is there any potential relationship between the two? Sugar can provide energy for the growth of cells in the body, including cancer cells. Consuming excessive amounts of sugar can increase the risk of developing cancer, including esophageal cancer. This is because excessive sugar intake can lead to weight gain, increasing the risk of obesity and diabetes, which can potentially trigger the occurrence of cancer.

How to diagnose diabetic nephropathy? The main basis for diagnosing diabetes is plasma glucose level, abbreviated as blood sugar. Generally, in clinical diagnosis criteria, venous plasma blood sugar is used, as fingertip blood sugar may have some errors, so it is not used as the main basis for diagnosing diabetes in clinical practice. Diabetic patients with fasting venous blood sugar > 7.0 mmol/L, or random blood sugar ≥ 11.1 mmol/L, can be diagnosed as diabetes. If further confirmation is desired, an oral glucose tolerance test can also be performed. The oral glucose tolerance test is the most commonly used test for diagnosing diabetes in clinical practice. It can reflect the fluctuation of blood sugar in patients, thereby helping us to make diagnoses and determine the level of blood sugar.

Why is the relationship between diabetes and cancer subtle? In type 2 diabetes patients who are obese, the level of insulin-like growth factor 1 is high. This factor is not only a multifunctional cell proliferation regulator, but also a tumor growth factor. Therefore, an increase in insulin levels also promotes tumor growth.

80% of type 2 diabetes patients are overweight or obese, with excessive accumulation of fat around their organs. Fat tissue produces high levels of fat factors, which can promote chronic inflammation and subsequently induce cancer. Cancer. In addition, cancer cells have a preference for carbohydrates and they take a large amount of sugar from the blood to supplement their energy, thereby causing continuous proliferation of cancer cells. After mutation, cancer cells significantly increase their ability to uptake glucose, up to 4-5 times higher than normal cells. Due to the higher blood sugar levels in diabetic patients, this further stimulates the proliferation of cancer cells, leading to the worsening or spreading of cancer.

Cancer is more common in patients with diabetes, especially type 2 diabetes. The types of cancer with the highest risk in diabetes patients are liver cancer, pancreatic cancer, and endometrial cancer, with a risk of over two times higher. The next highest risk is colorectal cancer, breast cancer, and bladder cancer, with a risk of 1.2 to 1.5 times higher. However, there is one exception, which is that the risk of developing prostate cancer is lower in male patients with type 2 diabetes.

Cancer There are also studies indicating that there may be age differences in the comorbidity of cancer and diabetes, such as 1% of newly diagnosed diabetes patients aged 50 and above developing pancreatic cancer within 3 years. Diabetes also increases the mortality rate of cancer. Compared to non-diabetic breast cancer patients, the risk of 5-year mortality rate is 1.39 times higher for diabetic patients with breast cancer. Diabetic patients with colorectal cancer have a 32% higher all-cause mortality rate compared to non-diabetic patients.

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