The latest treatment progress of type 2 diabetes.

This article discusses the knowledge points related to the latest treatment progress of type 2 diabetes, hoping to be helpful to you. Let's begin the formal explanation! What to do with type 2 diabetes? The reasonable treatment strategy for type 2 diabetes is "comprehensive", which not only includes blood glucose-lowering treatment but also requires blood pressure reduction, regulation of blood lipids, antiplatelet therapy, weight control, and improvement of lifestyle based on the individual complications of the patient.

Acute phase treatment The acute phase treatment of type 2 diabetes mainly refers to the occurrence of severe hyperglycemia and ketoacidosis. In general, immediate emergency treatment is needed, including rapid fluid replacement and correction of acid-base balance disorders. Type 2 diabetes may also cause hypoglycemia. Generally, self-administration of sugar water or consumption of high-sugar foods can alleviate it. However, if severe hypoglycemic reactions such as coma or consciousness disorders occur, immediate emergency treatment is required. The doctor will provide intravenous glucose supplementation and maintain vital signs.

General treatment For patients diagnosed with type 2 diabetes, general treatment strategies include controlling complications such as lowering blood glucose, reducing blood pressure, regulating blood lipids, and antiplatelet therapy. Additionally, controlling weight and improving lifestyle are also crucial.

Can type 2 diabetes be cured through surgery? For many adults, improper lifestyle habits can easily lead to the problem of diabetes. However, can the symptoms of type 2 diabetes be treated through surgery? Below, the author will provide a brief introduction for everyone. Currently, China has become the country with the highest number of diabetes patients in the world, with at least 20% of patients being moderately to severely obese.

In recent years, foreign researchers have found that surgeries originally used to treat morbid obesity have significant effects in improving diabetes in severely obese patients. Subsequent clinical studies have confirmed the effectiveness and safety of surgical treatment for obesity-related type 2 diabetes.

The International Diabetes Federation has officially issued a statement recognizing metabolic surgery as a method for treating type 2 diabetes. Compared to traditional treatment methods, weight loss surgeries not only effectively alleviate diabetes but also reduce weight, thereby improving various adverse consequences of obesity. Clinical data shows that the efficacy of surgical treatment for obesity-related type 2 diabetes weakens as the condition worsens, so surgery is advocated to be used earlier in suitable patients to achieve the best surgical results and prevent complications of diabetes.

However, surgical treatment for type 2 diabetes is not suitable for all patients and carries certain risks and postoperative complications. Clinical studies have shown that although the risk of death from weight loss surgery is lower than that of general surgery, there is still a certain mortality rate, and there may be short-term complications such as intestinal obstruction, anastomotic leakage, deep vein thrombosis, as well as long-term complications such as gallstones, gastric paresis, and malnutrition. Therefore, the use of surgical treatment for type 2 diabetes must strictly adhere to indications and contraindications.

Finally, the author would like to remind everyone to maintain a healthy lifestyle in their daily lives and develop good habits. However, for friends who have problems with type 2 diabetes, do not overly worry. The author suggests seeking timely treatment in a reputable hospital. Stem Cell Therapy for Type 2 Diabetes

Scientists have also been trying to find a treatment for type 2 diabetes, and they have ultimately chosen stem cells as a treatment option. Stem cells (MSCs) are chosen for diabetes treatment due to their convenient sourcing, easy collection, stable biological characteristics, low immunogenicity, no rejection reactions, no ethical issues, and the ability to differentiate into neuronal-like cells, insulin-producing beta cells, and reproductive cells under certain conditions.

Type 2 diabetes mellitus (T2DM) is characterized by impaired pancreatic β-cell function and varying degrees of insulin resistance, leading to the inability to maintain stable blood sugar levels. Cell replacement therapy is considered to have advantages in the intervention of diabetes mellitus (DM) and is believed to be an ideal candidate for intervening in diabetes mellitus.

Diabetes mellitus (DM) has caused significant harm to human life and health. In recent decades, it has become one of the major public health concerns worldwide. Diabetes has a high incidence and mortality rate among adult patients and is also a major risk factor for cardiovascular disease. Additionally, it can induce various organ complications such as retinopathy, neuropathy, and end-stage kidney disease, posing a huge threat to human life and health.

Diabetes is divided into three types: type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes. Among these, type 2 diabetes is a metabolic disorder related to age, caused by peripheral tissue insulin resistance and impaired pancreatic β-cell function, accounting for 90% to 95% of all diabetes cases.

Stem cell therapy provides new ideas for the intervention of type 2 diabetes. Currently, traditional interventions for type 2 diabetes include oral and injectable anti-diabetic drugs, which can alleviate hyperglycemia or temporarily improve insulin sensitivity in target tissues. However, these drugs cannot reverse insulin resistance or the progressive and inevitable dysfunction of beta cells. Therefore, developing new methods that can reverse insulin resistance and the progressive and inevitable dysfunction of beta cells is the key focus of diabetes intervention research.

With the extensive application of stem cells in the field of regenerative medicine, numerous studies have confirmed that stem cell therapy has low immunogenicity, immune regulation, and anti-apoptotic effects. Stem cell therapy can promote the regeneration of pancreatic beta cells, protect endogenous pancreatic beta cells from apoptosis, and improve peripheral tissue insulin resistance by providing a supportive microenvironment driven by the secretion of paracrine factors or the deposition of extracellular matrix. This reduces the risk of blood sugar and the occurrence of diabetes-related side effects, providing a new approach for intervention in type 2 diabetes.

Stem cell therapy intervenes in four characteristics of type 2 diabetes: 1. Stem cells have pluripotency, self-renewal ability, and immune response regulation ability. They can be induced to differentiate into insulin-producing cells (IPCs), promoting pancreatic regeneration and reducing insulin resistance. This provides an alternative approach for islet cell transplantation in the intervention of diabetes.

2. Promote the regeneration of pancreatic islet β cells: In addition to differentiating into insulin-producing cells (IPCs), stem cells can also migrate to damaged pancreatic islet cells and secrete various cell factors and growth factors with paracrine and autocrine activity to participate in the repair of pancreatic islet cells, thereby promoting the regeneration of pancreatic islet β cells.

3. Immunological characteristics: Stem cells have low immunogenicity and immunomodulatory properties, which can protect pancreatic islet β cells and reduce damage caused by autoimmune reactions. 4. Improve insulin resistance: By activating the insulin receptor substrate signaling pathway, high blood sugar can be improved, and insulin resistance in peripheral insulin target tissues can be relieved, achieving the goal of stabilizing blood sugar levels.

Stem cell therapy can effectively intervene in type 2 diabetes, depending on the rational optimization of intervention strategies and a comprehensive understanding of the intervention mechanism. The key lies in finding the appropriate cell delivery pathways and techniques, as well as the required cell types and quantities. With further research and relentless efforts from researchers, it is believed that stem cells will benefit more type 2 diabetes patients, restoring their health and enabling them to enjoy a happy life.

Why can't type 2 diabetes be cured? Generally speaking, diabetic patients rarely achieve recovery through medication. The majority of patients can only control their blood sugar through medication. Textbooks also describe diabetes as a chronic non-communicable disease that can only be controlled but not cured.

In recent years, with the development of medicine, metabolic surgery has gradually become one of the means of treating diabetes. In early 2021, an important paper on the progress of diabetes treatment was published online in The Lancet, which showed that for severe type 2 diabetic patients, metabolic surgery is more effective in long-term control of the disease than medication and lifestyle interventions, and more than one-third of surgical patients achieved long-term relief. This means that "cure" of type 2 diabetes is achievable.

Let's stop here with the introduction to the latest treatment advancements in type 2 diabetes. Thank you for taking the time to read the content on this website. Don't forget to search for more information about the latest treatment advancements in type 2 diabetes on this site.