The latest news on the cure for diabetes, the drug metformin.

Now let me tell you about the latest news on the cure for diabetes, the medicine called Metformin. I am happy to be able to help you and will now begin explaining. What medication is good for diabetes? The role of Sitagliptin Metformin tablets. Diabetes is a common metabolic disorder in modern society, mainly influenced by people's dietary habits. For diabetes patients, they need to control their sugar intake in their diet and also use medication to control blood sugar in a timely manner in order to avoid complications. So, what medication is good for diabetes? Sitagliptin Metformin tablets are very good.

1. Medication price The price of medication is associated with factors such as the medication's specifications and the location of its sales. When these factors change, the price naturally changes as well. The standard specifications for Sitagliptin Metformin tablets are 50mg/850mg * 28 tablets/box, and the price is 152.00 yuan. If patients purchase this medicine in first-tier cities such as Beijing or Shanghai, the price will increase, exceeding 160.00 yuan. However, in second or third-tier cities, the price will be slightly lower, mostly around 138.00 yuan.

2. How effective is it? According to reports, the main ingredient of Sitagliptin Metformin tablets is metformin hydrochloride, which is a white film-coated tablet. This medicine is mainly used for the treatment of diabetes, especially for diabetes patients who do not respond to dietary and exercise therapy. After taking this medication, it can effectively lower the patient's blood sugar and maintain it at a normal level for a long time. According to user feedback, the effect of this medicine is quite good and has been widely recognized by patients.

3. Correct usage In order to make the medication more effective, we must use it correctly. It is taken orally, two or three times a day, with one tablet each time. It can be taken during meals or after meals. In addition, we also need to pay attention to the side effects of the medication. Nausea, vomiting, and diarrhea are all side effects of the medicine, but these are relatively mild and will improve after a period of medication. Additionally, not all diabetes patients can take this medication. It is prohibited for patients with severe renal insufficiency or those who have a deficiency of folic acid or vitamin B12.

4. Medication precautions Sitagliptin Metformin tablets are very effective in treating diabetes, but they also have significant side effects. Some patients may experience hypoglycemia and gastrointestinal discomfort after taking this medication. Therefore, when taking this medication, regular medical check-ups should be done, and if severe side effects are found, the medication should be stopped immediately. Therefore, when using this medication to treat type 2 diabetes, it is necessary to consult a physician.

Sitagliptin Metformin tablets are prescription drugs and belong to chemically synthesized preparations. They can be considered as a type of hormone medication, so they should not be taken for a long time. They are taken orally. In fact, nursing care in the treatment of diabetes in daily life is more important, especially good dietary care.

5. Antidiabetic medications Looking at the elderly around us, many of them say they have diabetes and are frustrated because they cannot eat certain foods. Some people can effectively control their condition by paying attention to their diet, but others need medication for treatment. Nowadays, there are oral hypoglycemic agents, oral hypoglycemic sensitizers, alpha-glucosidase inhibitors, and other medications for diabetes treatment, as well as traditional Chinese medicine for oral hypoglycemia. However, it is important to note that the antihyperglycemic effect of Chinese medicine is weaker and slower compared to Western medicine.

In addition to the above medications, there are also medications for the treatment of diabetes such as thiazolidinediones and oral insulin. Although there are multiple medications available, it is also important to consider the type of diabetes one has. Insulin, which is familiar to many, also comes in different types, including short-acting, intermediate-acting, and long-acting. Therefore, it is best to follow the doctor's instructions when taking medication.

Why can metformin treat diabetes? Metformin is a classic drug in the field of diabetes treatment. It has been used in clinical practice for over 60 years. It is the first-line choice and lifelong medication for the treatment of type 2 diabetes. It is a core drug for diabetes prevention and treatment worldwide. However, some patients take acarbose. Which one between metformin and acarbose can lower blood sugar faster? Let's introduce it below.

Diabetic friends are familiar with metformin. Why can't its pharmaceutical status be shaken? Zhao Weigang, director of the Endocrinology Department of Beijing Hospital, summarized the three strongest points of metformin: good therapeutic effect, both as a monotherapy or in combination. When the therapeutic effect of metformin alone is not good, the use of other oral hypoglycemic drugs is not ruled out, which can further significantly improve blood sugar. It is highly safe, tested for over 60 years, and can be used by children aged 10 and above. Metformin can help lower blood pressure, blood lipids, and weight, which is also beneficial for cardiovascular protection. It has low treatment cost, and compared to other drugs with equivalent therapeutic effects, metformin is more economical in price.

Acarbose is irreplaceable. According to foreign reports, acarbose can reduce glycosylated hemoglobin by 1.3%, which means that it is particularly suitable for Asians who mainly consume carbohydrates. Acarbose has a highlight, which is that it mainly acts locally in the intestines, with only 1-2% being absorbed into the bloodstream. It has few systemic side effects such as liver and kidney damage and does not cause weight gain. Using this medication alone will not cause hypoglycemia and has a protective effect on the cardiovascular system. For diabetic patients, the main issues are postprandial hyperglycemia and overweight. This group of people is more suitable for lowering blood sugar by taking acarbose. In addition, elderly patients over the age of 65 can safely take it. There is insufficient information about the efficacy and tolerability of acarbose in adolescents under the age of 18, so it should not be used for patients under the age of 18. It is contraindicated for patients with allergies, diabetes and pre-coma, acidosis or ketosis; patients with significant gastrointestinal absorption disorders; patients with bloating and diseases that may worsen; and patients with severe liver dysfunction.

In conclusion, both Metformin and Acarbose have significant blood sugar lowering effects, and each has its own highlights. However, people with diabetes should not blindly take medication, but should choose a medication treatment plan based on their own circumstances under the guidance of a doctor in order to achieve the best treatment results.

Metformin can lower blood sugar, reduce lipid levels, promote weight loss, improve fatty liver, protect cardiovascular health, and reduce the risk of tumors. More and more evidence indicates that diabetes is a major risk factor for cardiovascular disease, so for hypoglycemic drugs, it is important to focus not only on achieving blood sugar control but also on emphasizing the effects beyond lowering blood sugar. Metformin is a typical representative in this regard.

Metformin mainly works by reducing hepatic glucose output (inhibiting the conversion of liver glycogen into glucose), reducing glucose absorption in the small intestine, improving insulin resistance, activating adenosine monophosphate-activated protein kinase, and promoting glucose oxidation and decomposition, thereby reducing blood sugar levels.

As a first-line treatment for diabetes, especially for overweight and obese patients with diabetes, metformin has been the preferred choice. It has a definite hypoglycemic effect and can lower fasting blood sugar and postprandial blood sugar. It can also reduce glycosylated hemoglobin levels by 1%-2%. The recommended starting dose is 500mg/day, the optimal effective dose is 2000mg/day, and the maximum dose is 2550mg/day.

When using metformin, it is recommended to start with the minimum dose and gradually increase to the optimal effective dose. If monotherapy at the maximum dose for 3 months still does not achieve blood sugar control, consider adding a second oral hypoglycemic drug. It can also be used in combination with insulin to further reduce insulin dosage and minimize the risk of weight gain and hypoglycemia caused by insulin.

One of the reasons metformin has an important role in the treatment of diabetes is its effects beyond lowering blood sugar. For example, it has lipid-lowering effects. Metformin can improve lipid synthesis and metabolism, and multiple studies have shown that it can reduce total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels in type 2 diabetes patients, but it has little effect on high-density lipoprotein cholesterol.

Metformin also has a weight-reducing effect. According to studies, after 4 months of monotherapy with metformin in newly diagnosed type 2 diabetes patients, the weight decreased by 1.47kg, 2.81kg, and 2.92kg for normal weight, overweight, and obese patients, respectively. The greater the body mass index and waist circumference, the more significant the weight loss after using metformin.

When using sulfonylureas (such as glimepiride), rosiglitazone, pioglitazone, and insulin for treatment, they often cause weight gain. Combining them with metformin can minimize the impact of these drugs on weight. Studies have shown that compared to insulin monotherapy, combining metformin with insulin can reduce weight gain by 2.28-3.85kg.

Metformin can also improve non-alcoholic fatty liver disease, including reducing alanine aminotransferase and aspartate aminotransferase levels, improving insulin resistance, and significantly improving liver inflammation, steatosis, and fibrosis. As long as the transaminase levels do not exceed three times the upper limit of normal and there is no severe liver dysfunction or decompensated cirrhosis, metformin can be used.

Metformin has a significant cardiovascular protective effect. It can reduce the risk factors for cardiovascular disease and protect the cardiovascular system. Controlling risk factors is an important measure to reduce cardiovascular events, including dyslipidemia, obesity, insulin resistance, hypertension, and non-alcoholic fatty liver. Metformin can lower blood sugar, blood lipids, body weight, improve insulin resistance (especially in the liver and muscles), and improve non-alcoholic fatty liver.

A 10-year follow-up study from the UK Prospective Diabetes Study showed that using metformin can reduce macrovascular complications and mortality, and this benefit is long-lasting. Its effect in reducing myocardial infarction and death is significantly better than sulfonylureas (such as glimepiride) and insulin. Therefore, it is suitable for patients with type 2 diabetes and concomitant cardiovascular diseases such as coronary heart disease, atherosclerosis, and arrhythmias.

In addition, metformin also has anti-tumor effects. Diabetes is a risk factor for breast cancer, pancreatic cancer, colorectal cancer, and endometrial cancer. Multiple studies have shown that metformin, through activating the adenosine monophosphate-activated protein kinase pathway, not only affects metabolism but also inhibits the occurrence and development of tumors. Metformin treatment can reduce the risk of lung cancer, prostate cancer, colorectal cancer, breast cancer, and other cancers.

In conclusion, there is conclusive evidence for the use of metformin in the treatment of type 2 diabetes and cardiovascular protection. It is also affordable, making it a suitable oral hypoglycemic drug for most patients with type 2 diabetes. Its goal is to lower fasting blood sugar, postprandial blood sugar, and glycosylated hemoglobin, and protect target organs such as the heart and kidneys, rather than assuming that more expensive drugs are better.

Can diabetes patients take metformin? In clinical practice, diabetes patients can take metformin orally to control blood sugar. Metformin is a first-line medication for type 2 diabetes. It works by inhibiting the output of liver glycogen, promoting the utilization of glucose in peripheral tissues, and controlling fasting and postprandial blood sugar levels, thereby better reducing glycated hemoglobin.

Metformin can also help with weight loss, regulate blood lipids, and have anti-atherosclerotic effects. Therefore, metformin is the preferred treatment for type 2 diabetes patients. If the gastrointestinal tract can tolerate it and there is no accompanying renal impairment, it is recommended to use metformin throughout the treatment.

The above is the complete knowledge points of the latest news on the cure for diabetes with the medication metformin. Hope it helps you.